Recent I-DOT publication:
Van Berkel et.al. report on “Immediate drop on demand technology (I-DOT) coupled with mass spectrometry via an open port sampling interface“. This immediate drop on demand technology/open port sampling interface/ESI–MS combination allowed for the quantitative analysis of relatively small mass analytes and was used for the identification of macromolecules like proteins.
Download the full paper at Future-Science: https://www.future-science.com/doi/full/10.4155/bio-2017-0104