Liquid Handler

Automated Liquid Handling:
The Future of Modern Laboratories
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What is a Liquid Handler?

A liquid handler is a fundamental laboratory instrument designed to accurately dispense, transfer, and mix a variety of liquid types in a controlled volume, ranging from microliters to milliliters. Liquid handlers can be manual, semi-automatic, or fully integrated automated systems, often using robotic pipetting technology to streamline repetitive tasks.

Advantages like improved precision, a reduction in human-error, and an increase in high-throughput workflows make liquid handlers at the forefront of modern laboratories, playing a critical role in supporting applications within pharmaceuticals, biotechnology, diagnostics, and drug discovery.  

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Dispensing

At DISPENDIX, we design fast, precise, and sustainable liquid handlers that streamline automated reagent dispensing across any application. Discover how our innovative solutions can transform your workflows. Explore our portfolio to learn more.

I.DOT: Our Non-Contact Liquid Handler

The I.DOT is the most innovative, non-contact liquid handler designed to streamline scientific workflows with a need for low volume automated reagent dispensing. This technology precisely dispenses volumes as low as 8nL with accuracy, speed, and without the use of traditional plastic pipette tips.

Additionally, with the I.DOT’s customizability and flexibility features, our technology will be installed to match your workflows, not the other way around. With a 0.1nL resolution, we enable our devices to perform reaction miniaturization, conserving reagents, and reducing dead volume.  

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Why the I.DOT?

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Multiple Liquid Handling Classes

Dispenses multiple liquid classes on demand, including aqueous solutions, PCR buffer, DMSO (up to 100%) and glycerol (up to 50%) — and defines liquid class at the well level.

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Non-Contact

Droplets are dispensed into the target plate below the source plate which eliminates carryover and cross-contamination.

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Speed

Dispenses 10 nanoliters across a 96-well plate in 10 seconds and across a 384-well plate in 20 seconds.

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Low Dead Volume

Further optimizes your workflow enabling assay miniaturization.

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G.PURE GEN 2: Automated, Reproducible & Tipless DNA Purification

G.PURE GEN 2 is engineered to streamline steps of the NGS library preparation workflow. By combining intuitive software with full PCR microplate compatibility, G.PURE eliminates the bottleneck of manual bead cleanups.

Built from the ground-up to make your NGS library preparation work easier, faster, and higher quality. The user-friendly, intuitive software, combined with being fully compatible with PCR microplates, makes implementing the G.PURE into your lab a breeze.

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Plate Washing

Our team is redefining the plate washer by integrating automated washing, precision dispensing, and intelligent data capture into a single, high-throughput solution. Discover how our systems can accelerate your workflows and help you achieve your research goals with greater speed, consistency, and control.

C.WASH PLUS

Sample washing steps consume a major portion of time in high-throughput library preparation applications. The C.WASH PLUS embeds centrifugal plate washing with a tip-free liquid handler, ideal for multi-reagent immune and cell-based assays in 96-, 384- and 1536-well plate formats.

This automated plate washing instrument achieves over 99.99% washing efficiency (after 2 wash cycles) with less than 0.1 µl residual volume in each well. Designed for ease of use, the C.WASH PLUS can be operated with minimal training, enabling rapid onboarding for new users. Additionally, liquid inputs, wash cycles, and target volumes can be flexibly configured, allowing users to tailor protocols to their specific assay requirements. 

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Transform Your Laboratory with Automated Liquid Handlers

Enhanced Accuracy and Precision 

Automated liquid handlers deliver highly precise and reproducible liquid transfers, even at very small volumes. This minimizes variability between samples and ensures consistent experimental outcomes, especially critical in applications such as drug discovery and genomics.  

Reduced Human Error 

Manual pipetting is prone to inconsistencies caused by fatigue, technique differences, and repetitive strain. Liquid handling automation eliminates many of these variables, leading to fewer errors and more dependable data.  

Time and Cost Efficiency 

By automating repetitive tasks, lab personnel can focus on higher-value activities such as data analysis and experimental design. Over time, this leads to reduced labor costs and improved overall productivity.  

Improved Reproducibility 

Consistency is essential in scientific research. Automated systems follow programmed protocols exactly, ensuring that experiments can be replicated with the same conditions across runs, users, and even different lab locations.

 Liquid handling automation plays a crucial role in modern laboratories by increasing efficiency, improving data quality, and enabling scalable, high throughput workflows.  

Learn From Our Liquid Handler Experts Today

Connect with our experts to find the right liquid handling solution for your workflow.  

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Frequently Asked Questions

What is a liquid handler?

A liquid handler is an automated laboratory instrument designed to precisely dispense, transfer, and mix liquids in workflows such as sample preparation, assay setup, and reagent distribution. 

How does a liquid handling system work?

Liquid handlers use pipetting technologies (air displacement, positive displacement, or non-contact dispensing) combined with robotic movement to transfer liquids between plates, tubes, or reservoirs.

What is the difference between contact and non-contact dispensing?

Contact dispensing touches the liquid surface or container, while non-contact dispensing (like acoustic or droplet-based systems) transfers liquid without physical contact, reducing contamination risk. 

Can liquid handlers handle viscous or volatile liquids?

Yes, but performance depends on the dispensing technology. Some systems are specifically designed to handle challenging liquids more effectively. The I.DOT includes a wide range of liquid classes that are optimized to dispense all kinds of reagents. 

Do liquid handlers require programming?

Some systems require scripting, while others offer user-friendly software with drag-and-drop interfaces. Our systems (I.DOT series), do not require any user programming and can be integrated into new or existing workflows from day 1. 

What is the future of liquid handling automation?

The future lies in miniaturization, increased automation, AI-driven workflows, and integration with fully autonomous labs.